Seeds Office Hours Episode 091 William Seeds, MD Jun 3, 2026 GLP-1 and the GutMusculoskeletal Axis: A Clinical Summary The Overlooked Connection: Dysbiosis and Degenerative Disease Degenerative musculoskeletal diseases, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc degeneration (IVDD), affect well over a billion people globally and share three core pathological features: chronic inflammation, oxidative stress, and dysregulated cell death
If youre struggling with a chronic condition such as heart disease, kidney dysfunction, fatty liver, or inflammatory bowel disease, GLP-1 medications may offer more than metabolic supportthey could help reduce inflammation and protect your long-term health
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Preventing Osteoporosis For bone health, B12 is essential as it contributes to bone density and strength
And importantly, if unintended weight loss occurs in a lean patient, we stop or lower the dose
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